Originea si evolutia cariotipului uman

CUPRINS:
NOTIUNI INTRODUCTIVE – Originea si evolutia
                                                 cariotipului           uman
p. 1.
CAPITOLUL I – Cariotipul uman normal                          p. 8.
        1. Relatare istorica                                        p. 8.
        2. Clasificarea cromozomilor nebandati  dupa  metode  conventionale
                                        p. 10.
        3. Nomenclatura cromozomilor mitotici bandati         p. 13.
        4. Polimorfismul cariotipului uman                    p. 25.
CAPITOLUL II – Aberatii cromozomiale umane                    p. 30.
                     2.1.             Aberatii           numeric-cromozomale
p. 30.
                             2.1.1.              Poliploidia           umana
p. 31.
                      2.1.2.      Aneuploidia   umana    si    nondisjunctia
p. 32.
                    2.2.            Aberatii          structural-cromozomale
p. 35.
                 1. Deletiile                                       p.  35.
                 2. Duplicatia                                p. 37.
                 3. Inversia                                        p. 37.
                 4. Translocatia                              p. 40.
                2.3.         Cauze      al      aberatiilor      cromozomale
p. 45.
CAPITOLUL III – Cromozomii sexului                            p. 47.
                3.1.        Originea     si      evolutia      heterozomilor
p. 47.
              3.2.      Baza    cromozomiala    a    determinarii    sexelor
p. 49.
        3. Cromozomul Y                                       p. 54.
                 3.3.1. Gena majora ce determina formarea  testiculelor   p.
      56.
        4.  Cromozomul X                                      p. 58.
CAPITOLUL IV – Sindroame heterozomale la om              p. 63.
                  4.1.           Sindromul       Klinefelter        (47,XXY)
p. 66.
            4.2.     Sindromul 47, XYY                              p. 72.
            4.3.     Sindromul 47,XXX                               p. 75.
                         4.4.                  Sindromul              Turner
p. 76.
                              4.5.                        Intersexualitatile
p. 81.
                                    4.5.1.                    Hermafrodismul
p. 81.
                  2. Pseudohermefrodismul                     p. 82.
                 4.6.          Sindromul       testiculului       feminizant
p. 85.
            4.7.     Sindromul X-fragil                             p. 88.